KP is a 24 that is receiving dexmethphenidate for ADHD. What are the monitoring parameters for efficacy and toxicity?

1.How does one differentiate between serotonin syndrome, neuroleptic malignant syndrome and malignant hyperthermia?
2.2. KO is a 15 yo receiving valproic acid. What are the indications for this medication and what are the monitoring parameters?
3. KP is a 24 that is receiving dexmethphenidate for ADHD. What are the monitoring parameters for efficacy and toxicity?
4. LK is a 34 yo receiving fentanyl IV. The nurse anesthetist notices he is becoming difficult to ventilate and has chest wall rigidity. Please explain this side effect to IV fentanyl?
5. Mk is a 65 yo with a DVT in the right leg.  To be started on warfarin. Currently on heparin? Why is it suggested that there be a 3-5 day overlap of the two meds despite the INR being therapeutic after 2 days?
6. TY is an NP student.  He is learning about warfarin. DO all disease states that require warfarin (stroke prevention, DVT treatment, post cardiac stent insertion) all require the same INR?   Please explain.
7. FT has a history of afib.  He saw a commercial for apixaban   and wants to know if he can use that vs warfarin.   What is this med and what are its indications for it.
Note; this a pharmacology class, pls go straight to the point. References should be current.

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