Review Chapter 19 in the Huether and McCance text and Chapter 18 in the Hammer and McPhee text. Identify the pathophysiology of diabetes mellitus and diabetes insipidus. Consider the similarities and differences between resulting alterations of hormonal regulation.

PATHOPHYSIOLOGY DISCUSSIONS

Special Instructions

  1. These are 3 different discussions
  2. For each discussion I need 1 page
  3. Please include sources that are less than 5 years
  4. Include at least one course material in each discussion
  5. Atleast 3 references are required for each discussion

Discussion 1: Digestive Disorders-1 page needed

Many patient symptoms can be tied to multiple disorders, which may lead to misdiagnoses. For instance, consider two digestive disorders of the gastrointestinal tract—inflammatory bowel disease and irritable bowel syndrome. These two disorders are commonly confused because they present similar symptoms. As an advanced practice nurse, you must know the differences to properly diagnose and treat the disorders. How does the pathophysiology of inflammatory bowel disease compare to the pathophysiology of irritable bowel syndrome? How do treatments for the two disorders compare?

To Prepare

  • Review Chapter 36 in the Huether and McCance text and Chapter 13 in the Hammer and McPhee text.
  • Identify the pathophysiological mechanisms of inflammatory bowel disease and irritable bowel syndrome. Think about similarities and differences between the disorders.
  • Consider common treatments for inflammatory bowel disease and irritable bowel syndrome. Reflect on whether treatments for one disorder would work for the other disorder.
  • Select one of the following patient factors: genetics, gender, ethnicity, age, or behavior. Reflect on how the factor you selected might impact the pathophysiology of and treatments for each disorder.

By Day 3

Post an explanation of the pathophysiological mechanisms of inflammatory bowel disorder and irritable bowel syndrome, including similarities and differences. Then describe common treatments, addressing whether treatments for one disorder would work for the other disorder. Finally, explain how the patient factor you selected might impact the pathophysiology of and treatments for each disorder.

Huether, S. E., & McCance, K. L. (2017). Understanding pathophysiology (6th ed.). St. Louis, MO: Mosby.

  • Chapter 35, “Structure and Function of the Digestive System”

This chapter provides information relating to the structure and function of the digestive system. It covers the gastrointestinal tract and accessory organs of digestion.

  • Chapter 36, “Alterations of Digestive Function”

This chapter presents information relating to disorders of the gastrointestinal tract and accessory organs of digestion. It also covers the pathogenesis, clinical manifestations, evaluation, and treatment of gastroesophageal reflux disease, gastritis, peptic ulcer disease, inflammatory bowel disease, and irritable bowel syndrome.

  • Chapter 37, “Alterations of Digestive Function in Children”

This chapter presents information relating to disorders of the gastrointestinal tract and liver that affect children. It focuses on congenital impairment, inflammatory disorders, metabolic disorders, as well as the impairment of digestion, absorption, and nutrition.

Hammer, G. D., & McPhee, S. J. (2019). Pathophysiology of disease: An introduction to clinical medicine (8th ed.). New York, NY: McGraw-Hill Education.

  • Chapter 13, “Gastrointestinal Disease”

This chapter provides a foundation for exploring gastrointestinal disorders by reviewing the structure and function of the GI tract. It also describes mechanisms of regulation of GI tract disorders such as acid-peptic disease, inflammatory bowel disease, and irritable bowel syndrome.

  • Chapter 14, “Liver Disease”

 

This chapter reviews the structure and function of the liver. It then explores the clinical presentation, etiology, pathogenesis, pathology, and clinical manifestations of three liver disorders: acute hepatitis, chronic hepatitis, and cirrhosis.

  • Chapter 15, “Disorders of the Exocrine Pancreas”

This chapter begins by reviewing the anatomy, histology, and physiology of the exocrine pancreas. It then examines the clinical presentation, etiology, pathology, pathogenesis, and clinical manifestations of acute and chronic pancreatitis, pancreatic insufficiency, and pancreatic cancer.

de Bortoli, N., Martinucci, I., Bellini, M., Savarino, E., Savarino, V., Blandizzi, C., & Marchi, S. (2013). Overlap of functional heartburn and gastroesophageal reflux disease with irritable bowel syndrome. World Journal of Gastroenterology, 19(35), 5787-5797. doi:10.3748/wjg.v19.i35.5787

Required Media

Laureate Education, Inc. (Executive Producer). (2012c). The gastrointestinal system. Baltimore, MD: Author.

 This media presentation outlines the pathophysiology of the gastrointestinal system and associated alterations.

Discussion 2: Diabetes-1 page needed

According to the American Diabetes Association (2011), 25.8 million children and adults have been diagnosed with diabetes in the United States. Approximately 2 million more are diagnosed every year, with another 79 million people considered to be in a pre-diabetes state. These millions of people are at risk of several alterations, including heart disease, stroke, kidney failure, neuropathy, and blindness. Since diabetes has a major impact on the health of millions of people around the world, it is essential for nurses to understand the pathophysiology and associated alterations of this disorder. In this Discussion, you compare two types of diabetes—diabetes mellitus and diabetes insipidus.

To Prepare

  • Review Chapter 19 in the Huether and McCance text and Chapter 18 in the Hammer and McPhee text. Identify the pathophysiology of diabetes mellitus and diabetes insipidus. Consider the similarities and differences between resulting alterations of hormonal regulation.
  • Select two of the following patient factors: genetics, gender, ethnicity, age, or behavior. Think about how the factors you selected might impact the diagnosis and prescription of treatment for these two types of diabetes.

By Day 3

Post an explanation of the pathophysiology of diabetes mellitus and diabetes insipidus. Describe the differences and similarities between resulting alterations of hormonal regulation. Then explain how the factors you selected might impact the diagnosis and prescription of treatment for these two types of diabetes.

Resources

Huether, S. E., & McCance, K. L. (2017). Understanding pathophysiology (6th ed.). St. Louis, MO: Mosby.

  • Chapter 18, “Mechanisms of Hormonal Regulation”

This chapter explores mechanisms of hormonal regulation and the structure and function of the endocrine glands. It provides a foundation for examining alterations of the endocrine system, as well as the effects of aging on the endocrine glands.

  • Chapter 19, “Alterations of Hormonal Regulation”

This chapter begins with an explanation of the mechanisms of hormonal alterations. It then discusses alterations of the hypothalamic-pituitary system, thyroid function, parathyroid function, endocrine pancreas, and adrenal function. It also covers the pathophysiology, clinical manifestations, and evaluation and treatment of type 1 and type 2 diabetes.

Hammer, G. D., & McPhee, S. J. (2019). Pathophysiology of disease: An introduction to clinical medicine (8th ed.). New York, NY: McGraw-Hill Education.

  • Chapter 17, “Disorders of the Parathyroids & Calcium & Phosphorus Metabolism”

This chapter explores the anatomy, histology, and associated mechanisms of the parathyroid glands, bone, vitamin D, and C cells. It then examines various disorders involving altered regulation of parathyroids, calcium, and phosphorous metabolism.

  • Chapter 18, “Disorders of the Endocrine Pancreas”

This chapter explores the anatomy, histology, and physiology of the endocrine pancreas. It then covers the clinical presentation, etiology, pathophysiology, and clinical manifestations of endocrine pancreas disorders such as diabetes mellitus.

  • Chapter 19, “Disorders of the Hypothalamus & Pituitary Gland”

This chapter covers the structure and function of the hypothalamus and pituitary glands. It then explores disorders relating to alterations of the hypothalamus and pituitary glands.

  • Chapter 20, “Thyroid Disease”

This chapter explains thyroid hormones, including how they are formed and secreted. It then examines thyroid diseases such as hyperthyroidism, hypothyroidism, and goiters.

Optional Resources

American Diabetes Association. (2012). Retrieved from http://www.diabetes.org/

The Endocrine Society. (2012). Retrieved from http://www.endo-society.org/

The Hormone Foundation. (2012). Retrieved from http://www.hormone.org/

Discussion 3 : Urinary Tract Infections-1 page needed

Urinary tract infections (UTIs) are caused by bacteria—most often Escherichia coli. However, certain viruses, fungi, and parasites can also lead to infection. The infection can affect the lower and upper urinary tract, including the urethra, prostate (in males), bladder, ureter, and kidney. Due to the progression of the disease and human anatomy, symptoms present differently among the sexes as well as among age groups. It is important to understand how these factors, as well as others, impact the pathophysiology of UTIs. Advanced practice nurses must have this foundation in order to properly diagnose patients.

To Prepare

  • Review Chapter 30 in the Huether and McCance text. Identify the pathophysiology of lower and upper urinary tract infections. Consider the similarities and differences between the two types of infections.
  • Select two of the following patient factors: genetics, gender, ethnicity, age, or behavior. Reflect on how the factors you selected might impact the pathophysiology of the infections, as well as the diagnosis of and treatment for the infections.

By Day 3

Post a description of the pathophysiology of lower and upper urinary tract infections, including their similarities and differences. Then explain how the factors you selected might impact the pathophysiology of the infections, as well as the diagnosis of and treatment for the infections.

Huether, S. E., & McCance, K. L. (2017). Understanding pathophysiology (6th ed.). St. Louis, MO: Mosby.

  • Chapter 29, “Structure and Function of the Renal and Urologic Systems”

This chapter introduces the structure and function of the renal and urologic systems. It covers renal blood flow, kidney function, and tests for renal and bladder function.

 

  • Chapter 30, “Alterations of Renal and Urinary Tract Function”

This chapter examines alterations of the renal and urinary tract function, including urinary tract obstruction, urinary tract infection, acute kidney injury, and chronic kidney disease. It focuses on the pathophysiology, clinical manifestation, and evaluation and treatment of those renal and urinary tract alterations.

  • Chapter 31, “Alterations of Renal and Urinary Tract Function in Children”

This chapter presents alterations of renal and urinary tract function that are common in children. These alterations include structural abnormalities, bladder disorders, nephroblastoma, and urinary incontinence.

Hammer, G. D., & McPhee, S. J. (2019). Pathophysiology of disease: An introduction to clinical medicine (8th ed.). New York, NY: McGraw-Hill Education.

  • Chapter 16, “Renal Disease”

This chapter explores the structure and function of the kidney for preparation of examining renal diseases. It then examines renal diseases such as acute kidney injury and chronic renal failure.

Optional Resources

 

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