In women diagnosed with subclinical hypothyroidism at the realization of pregnancy, does treatment with levothyroxine for TSH greater than 2.5mlU/L reduces the risk of spontaneous abortion within the first trimester?

Please do research on how to conduct a meta-analysis review to answer this section.
Submit a draft of Section 2 of the Methods section of your project. Remember that should include the following information:
• Instruments: What instruments will you use? What evidence or research exists for the instruments? Have they been determined to be valid or reliable? If so, for what groups? If you are using an instrument or tool that has not been well studied, ensure that you provide evidence to justify its use in your project.
• Data Collection: Are there any other points of data that you will be collecting that have not previously been mentioned? The emphasis in this section should be on fully describing specifically what data you will be using in your study. Part of the purpose of doing this is to detect flaws in the plan before they become problems in the research.
• Data Analysis Plan: How will you analyze your data? This section should explain in some detail how you will manipulate the data that you assembled to get at the information that you will use to answer your question. When describing statistical tests, ensure that you have specified the appropriate information, such as significance level and type of confidence interval (one or two sided). Additionally, describe what meaning the “output” of any statistical tests will help answer and how it relates to your PICOT/clinical problem.

Research question: In women diagnosed with subclinical hypothyroidism at the realization of pregnancy, does treatment with levothyroxine for TSH greater than 2.5mlU/L reduces the risk of spontaneous abortion within the first trimester?

The data to perform the measurements for this project will be obtained using data from previously completed studies related to the topic of interest. All studies are peer-reviewed articles published in scholarly journals and consist of many design types, models, and frameworks.

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